4 papers
Act Like a Pathologist: Tissue-Aware Whole Slide Image Reasoning
Wentao Huang, Weimin Lyu, Peiliang Lou +8
Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-langua…
Multimodal Alignment of Histopathological Images Using Cell Segmentation and Point Set Matching for Integrative Cancer Analysis
Jun Jiang, Raymond Moore, Brenna Novotny +5
Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary ins…
Assessing Reusability of Deep Learning-Based Monotherapy Drug Response Prediction Models Trained with Omics Data
Jamie C. Overbeek, Alexander Partin, Thomas S. Brettin +21
Cancer drug response prediction (DRP) models present a promising approach towards precision oncology, tailoring treatments to individual patient profiles. While deep learning (DL)…
Variational and Explanatory Neural Networks for Encoding Cancer Profiles and Predicting Drug Responses
Tianshu Feng, Rohan Gnanaolivu, Abolfazl Safikhani +7
Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes m…