299 citations · 596 across the 16 of their papers we have counts for
16 papers
Stochastic epigenetic dynamics of gene switching
Bhaswati Bhattacharyya, Jin Wang, Masaki Sasai
Epigenetic modifications of histones crucially affect the eukaryotic gene activity, while the epigenetic histone state is largely determined by the binding of specific factors such…
Organization of fast and slow chromatin revealed by single-nucleosome dynamics
S. S. Ashwin, Tadasu Nozaki, Kazuhiro Maeshima +1
Understanding chromatin organization and dynamics is important since they crucially affect DNA functions. In this study, we investigate chromatin dynamics by statistically analyzin…
Single-molecular and Ensemble-level Oscillations of Cyanobacterial Circadian Clock
Sumita Das, Tomoki P. Terada, Masaki Sasai
When three cyanobacterial proteins, KaiA, KaiB, and KaiC, are incubated with ATP in vitro, the phosphorylation level of KaiC hexamers shows stable oscillation with approximately 24…
Cooperativity and modularity in protein folding
Masaki Sasai, George Chikenji, Tomoki P. Terada
A simple statistical mechanical model proposed by Wako and Sait has explained the aspects of protein folding surprisingly well. This model was systematically applied t…
Epigenetic Dynamics of Cell Reprogramming
S. S. Ashwin, Masaki Sasai
Reprogramming is a process of transforming differentiated cells into pluripotent stem cells by inducing specific modifying factors in the cells. Reprogramming is a non-equilibrium…
Cortical Factor Feedback Model for Cellular Locomotion and Cytofission
Shin I. Nishimura, Masahiro Ueda, Masaki Sasai
Eukaryotic cells can move spontaneously without being guided by external cues. For such spontaneous movements, a variety of different modes have been observed, including the amoebo…