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physics.bio-ph2024
Liquid-liquid phase separation of proteins is modulated by amino acids in vitro and in vivo by regulating protein-protein interactions
Xufeng Xu, Aleksander A. Rebane, Laura R. Julia +3
Liquid liquid phase separation (LLPS) of proteins is an intracellular process that is widely used by cells for many purposes. In living cells (in vivo), LLPS occurs in complex and…
physics.bio-ph2024
Amino Acids and Their Biological Derivatives Modulate Protein-Protein Interactions In an Additive Way
Xufeng Xu, Francesco Stellacci
Protein-protein interactions (PPI) differ when measured in test tubes and cells due to the complexity of the intracellular environment. Free amino acids (AAs) and their derivatives…