124 citations · 837 across the 31 of their papers we have counts for
5 papers · 1 filter
Impact of a non-uniform charge distribution on virus assembly
Siyu Li, Gonca Erdemci-Tandogan, Jef Wagner +2
Many spherical viruses encapsulate their genome in protein shells with icosahedral symmetry. This process is spontaneous and driven by electrostatic interactions between positive d…
In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway
Jiying Ning, Gonca Erdemci-Tandogan, Ernest L Yufenyuy +6
HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature i…
Role of Genome in the Formation of Conical Retroviral Shells
Gonca Erdemci-Tandogan, Jef Wagner, Paul van der Schoot +1
Human immunodeficiency virus (HIV) capsid proteins spontaneously assemble around the genome into a protective protein shell called the capsid, which can take on a variety of shapes…
Effects of RNA branching on the electrostatic stabilization of viruses
Gonca Erdemci-Tandogan, Jef Wagner, Paul van der Schoot +2
Many single-stranded (ss) RNA viruses self assemble from capsid protein subunits and the nucleic acid to form an infectious virion. It is believed that the electrostatic interactio…
RNA topology remolds electrostatic stabilization of viruses
Gonca Erdemci-Tandogan, Jef Wagner, Paul van der Schoot +2
Simple RNA viruses efficiently encapsulate their genome into a nano-sized protein shell: the capsid. Spontaneous co-assembly of the genome and the capsid proteins is driven predomi…