69 citations · 1.1k across the 120 of their papers we have counts for
4 papers · 1 filter
Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs
Suleiman A. Khan, Ali Faisal, John Patric Mpindi +6
Detailed and systematic understanding of the biological effects of millions of available compounds on living cells is a significant challenge. As most compounds impact multiple tar…
Bayesian Group Factor Analysis
Seppo Virtanen, Arto Klami, Suleiman A. Khan +1
We introduce a factor analysis model that summarizes the dependencies between observed variable groups, instead of dependencies between individual variables as standard factor anal…
RPA: Probabilistic analysis of probe performance and robust summarization
Leo Lahti, Laura L. Elo, Tero Aittokallio +1
Probe-level models have led to improved performance in microarray studies but the various sources of probe-level contamination are still poorly understood. Data-driven analysis of…
Dependency detection with similarity constraints
Leo Lahti, Samuel Myllykangas, Sakari Knuutila +1
Unsupervised two-view learning, or detection of dependencies between two paired data sets, is typically done by some variant of canonical correlation analysis (CCA). CCA searches f…