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physics.bio-ph2024★ 3 cited
Comparing AI versus Optimization Workflows for Simulation-Based Inference of Spatial-Stochastic Systems
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Model parameter inference is a universal problem across science. This challenge is particularly pronounced in developmental biology, where faithful mechanistic descriptions require…
physics.bio-ph2024
AI-powered simulation-based inference of a genuinely spatial-stochastic model of early mouse embryogenesis
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a central challenge in developmental biology. This is particularly intriguing in early mammali…