3 citations · 3 across the 4 of their papers we have counts for
4 papers
Information-Theoretical Measures for Developmental Cell-Fate Proportioning Processes
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Self-organization is a fundamental process of complex biological systems, particularly during the early stages of development. In the mammalian embryo, blastocyst formation exempli…
Initial Luminally Deposited FGF4 Critically Influences Blastocyst Patterning
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Luminogenesis, the formation of a fluid-filled cavity (lumen), is an essential process in early mammalian embryonic development, coinciding with the second cell-fate decision that…
Comparing AI versus Optimization Workflows for Simulation-Based Inference of Spatial-Stochastic Systems
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Model parameter inference is a universal problem across science. This challenge is particularly pronounced in developmental biology, where faithful mechanistic descriptions require…
AI-powered simulation-based inference of a genuinely spatial-stochastic model of early mouse embryogenesis
Michael A. Ramirez-Sierra, Thomas R. Sokolowski
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a central challenge in developmental biology. This is particularly intriguing in early mammali…