33 citations · 37 across the 8 of their papers we have counts for
8 papers
Variants of intrinsic disorder in the human proteome
Antonio Deiana, Andrea Giansanti
In this paper we propose a straightforward operational definition of variants of disordered proteins, taking the human proteome as a case study. The focus is on a distinction betwe…
Codon Bias Patterns of 's Interacting Proteins
Maddalena Dilucca, Giulio Cimini, Andrea Semmoloni +2
Synonymous codons, i.e., DNA nucleotide triplets coding for the same amino acid, are used differently across the variety of living organisms. The biological meaning of this phenome…
On the abundance of intrinsically disordered proteins in the human proteome and its relation to diseases: there is no enrichment
Antonio Deiana, Andrea Giansanti
Intrinsically disordered proteins are fascinating the community of protein science since the last decade, at least. There is a well-established line of research that intends to rev…
Is the unfoldome widespread in proteomes?
Antonio Deiana, Andrea Giansanti
The term unfoldome has been recently used to indicate the universe of intrinsically disordered proteins. These proteins are characterized by an ensemble of high-flexible interchang…
Amino acid composition and thermal stability of protein structures: the free energy geography of the Protein Data Bank
Antonio Deiana, Kana Shimizu, Andrea Giansanti
We study the combined influence of amino acid composition and chain length on the thermal stability of protein structures. A new parameterization of the internal free energy is con…
Combining predictors of natively unfolded proteins to detect a twilight zone between order and disorder in generic datasets
Antonio Deiana, Andrea Giansanti
Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-function paradigm. M…