286 citations · 1.9k across the 27 of their papers we have counts for
4 papers · 1 filter
Twirling of actin by myosins II and V observed via polarized TIRF in a modified gliding assay
John F. Beausang, Harry W. Schroeder, Philip C. Nelson +1
The force generated between actin and myosin acts predominantly along the direction of the actin filament, resulting in relative sliding of the thick and thin filaments in muscle o…
The role of microtubule movement in bidirectional organelle transport
Igor M. Kulić, André E. X. Brown, Hwajin Kim +5
We study the role of microtubule movement in bidirectional organelle transport in Drosophila S2 cells and show that EGFP-tagged peroxisomes in cells serve as sensitive probes of mo…
Concentration and Length Dependence of DNA Looping in Transcriptional Regulation
Lin Han, Hernan G. Garcia, Seth Blumberg +4
In many cases, transcriptional regulation involves the binding of transcription factors at sites on the DNA that are not immediately adjacent to the promoter of interest. This acti…
First-principles calculation of DNA looping in tethered particle experiments
Kevin B. Towles, John F. Beausang, Hernan G. Garcia +2
We calculate the probability of DNA loop formation mediated by regulatory proteins such as Lac repressor (LacI), using a mathematical model of DNA elasticity. Our model is adapted…