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stat.ME2026
Two-dose vs. Three-Dose Optimization Under Sample Size Constraint
Linda Sun, Yixin Ren, Cong Chen
Dose optimization is a hallmark of Project Optimus for oncology drug development. The number of doses to include in a dose optimization study depends on the totality of evidence, w…
stat.ME2023★ 1 cited
Adjusted inference for multiple testing procedure in group sequential designs
Yujie Zhao, Qi Liu, Linda Z. Sun +1
Adjustment of statistical significance levels for repeated analysis in group sequential trials has been understood for some time. Similarly, methods for adjustment accounting for t…