1 citations · 1 across the 4 of their papers we have counts for
4 papers
Two-dose vs. Three-Dose Optimization Under Sample Size Constraint
Linda Sun, Yixin Ren, Cong Chen
Dose optimization is a hallmark of Project Optimus for oncology drug development. The number of doses to include in a dose optimization study depends on the totality of evidence, w…
Advancing Waterfall Plots for Cancer Treatment Response Assessment through Adjustment of Incomplete Follow-Up Time
Zhe, Wang, Linda Z. Sun +1
Waterfall plots are a key tool in early phase oncology clinical studies for visualizing individual patients' tumor size changes and provide efficacy assessment. However, comparing…
Generalized Design of Basket Trials with P-value Combination Test
Heng Zhou, Linda Sun, Fang Liu +1
The oncology exploratory basket trial design with pruning and pooling (P&P) approach has gained increasing popularity in recent years for its simplicity and efficiency. This method…
Adjusted inference for multiple testing procedure in group sequential designs
Yujie Zhao, Qi Liu, Linda Z. Sun +1
Adjustment of statistical significance levels for repeated analysis in group sequential trials has been understood for some time. Similarly, methods for adjustment accounting for t…