activity
20082022
most citedRefolding dynamics of stretched biopolymers upon force quench

50 citations · 110 across the 6 of their papers we have counts for

collaborators

6 papers

math.NT2022

Relative Ideal Classes of Arbitrary Order

David L. Pincus, Lawrence C. Washington

We adapt a known technique for searching for ideal classes of arbitrary order and then apply it to three families of number fields. We show that a family of cyclic sextic number fi…

q-bio.BM2015★ 22 cited

Helicase processivity and not the unwinding velocity exhibits universal increase with force

David L. Pincus, Shaon Chakrabarti, D. Thirumalai

Helicases, involved in a number of cellular functions, are motors that translocate along singlestranded nucleic acid and couple the motion to unwinding double-strands of a duplex n…

q-bio.BM2013★ 1 cited

Force-Induced Unzipping Transitions in an Athermal Crowded Environment

David L. Pincus, D. Thirumalai

Using theoretical arguments and extensive Monte Carlo (MC) simulations of a coarse-grained three-dimensional off-lattice model of a β-hairpin, we demonstrate that the equilibrium c…

physics.bio-ph2009★ 50 cited

Refolding dynamics of stretched biopolymers upon force quench

Changbong Hyeon, Greg Morrison, David L. Pincus +1

Single molecule force spectroscopy methods can be used to generate folding trajectories of biopolymers from arbitrary regions of the folding landscape. We illustrate the complexity…

q-bio.BM2008★ 35 cited

Crowding effects on the mechanical stability and unfolding pathways of Ubiquitin

David L. Pincus, D. Thirumalai

The interior of cells is crowded thus making it important to assess the effects of macromolecules on the folding of proteins. Using the Self-Organized Polymer (SOP) model, which is…

q-bio.BM2008★ 2 cited

Minimal models for proteins and RNA: From folding to function

D. L. Pincus, S. S. Cho, C. Hyeon +1

We present a panoramic view of the utility of coarse-grained (CG) models to study folding and functions of proteins and RNA. Drawing largely on the methods developed in our group o…