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Dynamical quorum-sensing and synchronization of nonlinear oscillators coupled through an external medium
David J. Schwab, Ania Baetica, Pankaj Mehta
Many biological and physical systems exhibit population-density dependent transitions to synchronized oscillations in a process often termed "dynamical quorum sensing". Synchroniza…
Statistical mechanics of transcription-factor binding site discovery using Hidden Markov Models
Pankaj Mehta, David Schwab, Anirvan M. Sengupta
Hidden Markov Models (HMMs) are a commonly used tool for inference of transcription factor (TF) binding sites from DNA sequence data. We exploit the mathematical equivalence betwee…
Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell
Shu-Wen Teng, Yufang Wang, Kimberly C. Tu +5
Quorum sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-s…