2 papers
stat.AP2023
Incorporating patient-reported outcomes in dose-finding clinical trials with continuous patient enrollment
Anaïs Andrillon, Lucie Biard, Shing M. Lee
Dose-finding clinical trials in oncology aim to estimate the maximum tolerated dose (MTD), based on safety traditionally obtained from the clinician's perspective. While the collec…
stat.AP2023
Precision Dose-finding Cancer Clinical Trials in the Setting of Broadened Eligibility
Rebecca B. Silva, Bin Cheng, Richard D. Carvajal +1
Broadening eligibility criteria in cancer trials has been advocated to represent the true patient population more accurately. While the advantages are clear in terms of generalizab…