4 citations · 7 across the 16 of their papers we have counts for
4 papers · 1 filter
Model-free Approach to Evaluate a Censored Intermediate Outcome as a Surrogate for Overall Survival
Xuan Wang, Tianxi Cai, Lu Tian +1
Clinical trials or studies oftentimes require long-term and/or costly follow-up of participants to evaluate a novel treatment/drug/vaccine. There has been increasing interest in th…
Semiparametric Joint Modeling to Estimate the Treatment Effect on a Longitudinal Surrogate with Application to Chronic Kidney Disease Trials
Xuan Wang, Jie Zhou, Layla Parast +1
In clinical trials where long follow-up is required to measure the primary outcome of interest, there is substantial interest in using an accepted surrogate outcome that can be mea…
Group Sequential Testing of a Treatment Effect Using a Surrogate Marker
Layla Parast, Jay Bartroff
The identification of surrogate markers is motivated by their potential to make decisions sooner about a treatment effect. However, few methods have been developed to actually use…
Robust Evaluation of Longitudinal Surrogate Markers with Censored Data
Denis Agniel, Layla Parast
The development of statistical methods to evaluate surrogate markers is an active area of research. In many clinical settings, the surrogate marker is not simply a single measureme…