activity
20222026
most citedStatistical and Practical Considerations in Planning and Conduct of Dose Optimization Trials

1 citations · 1 across the 6 of their papers we have counts for

collaborators
Showing stat.APShow all

1 paper · 1 filter

stat.AP2026

A Utility Score Framework for Dose Optimization Studies with Binary Efficacy-Safety Endpoints: Sample Size Determination and Bias Characterization

Xuemin Gu, Cong Xu, Lei Xu +1

The FDA's Project Optimus initiative emphasizes patient-centered dose selection in oncology that balances efficacy and safety. We develop a framework for randomized dose optimizati…