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q-bio.BM2025
Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia
Jian Jiang, Long Chen, Yueying Zhu +5
Anesthetics are crucial in surgical procedures and therapeutic interventions, but they come with side effects and varying levels of effectiveness, calling for novel anesthetic agen…
q-bio.BM2023
Machine Learning Study of the Extended Drug-target Interaction Network informed by Pain Related Voltage-Gated Sodium Channels
Long Chen, Jian Jiang, Bozheng Dou +6
Pain is a significant global health issue, and the current treatment options for pain management have limitations in terms of effectiveness, side effects, and potential for addicti…
q-bio.BM2022
TIDAL: Topology-Inferred Drug Addiction Learning
Zhu Zailiang, Dou Bozheng, Cao Yukang +8
Drug addiction or drug overdose is a global public health crisis, and the design of anti-addiction drugs remains a major challenge due to intricate mechanisms. Since experimental d…