3 papers
physics.bio-ph2023
Stress-shape misalignment in confluent cell layers
Mehrana R. Nejad, Liam J. Ruske, Molly McCord +4
This study investigates the relationship between cell shape and cell-generated stresses in confluent cell layers. Using simultaneous measurements of cell shape orientation and cell…
cond-mat.soft2023
Active nematics with deformable particles
Ioannis Hadjifrangiskou, Liam J. Ruske, Julia M. Yeomans
The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues.…
cond-mat.soft2022
Activity-driven tissue alignment in proliferating spheroids
Liam J Ruske, Julia M Yeomans
We extend the continuum theory of active nematic fluids to study cell flows and tissue dynamics inside multicellular spheroids, spherical, self-assembled aggregates of cells that a…