41 citations · 47 across the 6 of their papers we have counts for
6 papers
Stress-shape misalignment in confluent cell layers
Mehrana R. Nejad, Liam J. Ruske, Molly McCord +4
This study investigates the relationship between cell shape and cell-generated stresses in confluent cell layers. Using simultaneous measurements of cell shape orientation and cell…
Active nematics with deformable particles
Ioannis Hadjifrangiskou, Liam J. Ruske, Julia M. Yeomans
The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues.…
Activity-driven tissue alignment in proliferating spheroids
Liam J Ruske, Julia M Yeomans
We extend the continuum theory of active nematic fluids to study cell flows and tissue dynamics inside multicellular spheroids, spherical, self-assembled aggregates of cells that a…
Activity gradients in two- and three-dimensional active nematics
Liam J Ruske, Julia M Yeomans
We numerically investigate how spatial variations of extensile or contractile active stress affect bulk active nematic systems in two and three dimensions. In the absence of defect…
Morphology of active deformable 3D droplets
Liam J. Ruske, Julia M. Yeomans
We numerically investigate the morphology and disclination line dynamics of active nematic droplets in three dimensions. Although our model only incorporates the simplest possible…
Coupled differentiation and division of embryonic stem cells inferred from clonal snapshots
Liam J. Ruske, Jochen Kursawe, Anestis Tsakiridis +4
The deluge of single-cell data obtained by sequencing, imaging and epigenetic markers has led to an increasingly detailed description of cell state. However, it remains challenging…