activity
20222024
most citedGenome-wide networks reveal emergence of epidemic strains of Salmonella Enteritidis

13 citations · 13 across the 2 of their papers we have counts for

collaborators

6 papers

q-bio.QM2024

Impact of opinion dynamics on recurrent pandemic waves: balancing risk aversion and peer pressure

Sheryl L. Chang, Quang Dang Nguyen, Carl J. E. Suster +6

Recurrent waves which are often observed during long pandemics typically form as a result of several interrelated dynamics including public health interventions, population mobilit…

q-bio.GN2023

High Performance Multiple Sequence Alignment Algorithms for Comparison of Microbial Genomes

Manal Helal, Hossam El-Gindy, Bruno Gaeta +1

Advances in gene sequencing have enabled in silico analyses of microbial genomes and have led to the revision of concepts of microbial taxonomy and evolution. We explore deficienci…

q-bio.GN2023

Defining Reference Sequences for Nocardia Species by Similarity and Clustering Analyses of 16S rRNA Gene Sequence Data

Manal Helal, Fanrong Kong, Sharon C. A. Chen +3

The intra- and inter-species genetic diversity of bacteria and the absence of 'reference', or the most representative, sequences of individual species present a significant challen…

q-bio.GN2023

Linear normalised hash function for clustering gene sequences and identifying reference sequences from multiple sequence alignments

Manal Helal, Fanrong Kong, Sharon C-A Chen +4

The aim of this study was to develop a method that would identify the cluster centroids and the optimal number of clusters for a given sensitivity level and could work equally well…

q-bio.GN2023

Dynamic Programming Algorithms for Discovery of Antibiotic Resistance in Microbial Genomes

Manal Helal, Vitali Sintchenko

The translation of comparative genomics into clinical decision support tools often depends on the quality of sequence alignments. However, currently used methods of multiple sequen…

q-bio.QM202213 cited

Genome-wide networks reveal emergence of epidemic strains of Salmonella Enteritidis

Adam J. Svahn, Sheryl L. Chang, Rebecca J. Rockett +7

Objectives: To enhance monitoring of high-burden foodborne pathogens, there is opportunity to combine pangenome data with network analysis. Methods: Salmonella enterica subspecies…