2 papers
q-bio.BM2009★ 33 cited
Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly
Zhanghan Wu, Hong-Wei Wang, Weihua Mu +3
The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet po…
q-bio.BM2009★ 12 cited
Amplification and detection of single molecule conformational fluctuation through a protein interaction network with bimodal distributions
Zhanghan Wu, Vlad Elgart, Hong Qian +1
A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe thi…