33 citations · 80 across the 5 of their papers we have counts for
6 papers
Global Epigenetic State Network Governs Cellular Pluripotent Reprogramming and Transdifferentiation
Ping Wang, Chaoming Song, Hang Zhang +2
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin sta…
Network Topologies and Dynamics Leading to Endotoxin Tolerance and Priming in Innate Immune Cells
Yan Fu, Trevor Glaros, Meng Zhu +5
The innate immune system, acting as the first line of host defense, senses and adapts to foreign challenges through complex intracellular and intercellular signaling networks. Endo…
Coupling between switching regulation and torque generation in bacterial flagellar motor
Fan Bai, Tohru Minamino, Zhanghan Wu +2
The bacterial flagellar motor plays a crucial role in both bacterial locomotion and chemotaxis. Recent experiments reveal that the switching dynamics of the motor depends on the mo…
Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly
Zhanghan Wu, Hong-Wei Wang, Weihua Mu +3
The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet po…
Amplification and detection of single molecule conformational fluctuation through a protein interaction network with bimodal distributions
Zhanghan Wu, Vlad Elgart, Hong Qian +1
A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe thi…
Optimizing Optical Quantum Logic Gates using Genetic Algorithms
Zhanghan Wu, Sean D. Huver, Dmitry Uskov +2
We introduce the method of using an annealing genetic algorithm to the numerically complex problem of looking for quantum logic gates which simultaneously have highest fidelity and…