4 papers
Machine learning traction force maps of cell monolayers
Changhao Li, Luyi Feng, Yang Jeong Park +3
Cellular force transmission across a hierarchy of molecular switchers is central to mechanobiological responses. However, current cellular force microscopies suffer from low throug…
Mechano-lithography: stress anisotropy driven nematic order in growing three-dimensional bacterial biofilms
Changhao Li, Japinder Nijjer, Luyi Feng +3
Living active collectives have evolved with remarkable self-patterning ability to meet the physical and biological constraints for growth and survival. However, how complex multice…
Biofilms as self-shaping growing nematics
Japinder Nijjer, Mrityunjay Kothari, Changhao Li +7
Active nematics are the nonequilibrium analog of passive liquid crystals in which anisotropic units consume free energy to drive emergent behavior. Similar to liquid crystal (LC) m…
Biofilm self-patterning: mechanical forces drive a reorientation cascade
Japinder Nijjer, Changhao Li, Qiuting Zhang +3
In growing active matter systems, a large collection of engineered or living autonomous units metabolize free energy and create order at different length scales as they proliferate…