2 citations · 4 across the 5 of their papers we have counts for
5 papers
Recognition and reconstruction of cell differentiation patterns with deep learning
Robin Dirk, Jonas L. Fischer, Simon Schardt +2
Cell lineage decisions occur in three-dimensional spatial patterns that are difficult to identify by eye. There is an ongoing effort to replicate such patterns using mathematical m…
Adjusting the range of cell-cell communication enables fine-tuning of cell fate patterns from checkerboard to engulfing
Simon Schardt, Sabine C. Fischer
During development, spatio-temporal patterns ranging from checkerboard to engulfing occur with precise proportions of the respective cell fates. Key developmental regulators are in…
Global cell-cell communication enables spatial segregation of cells in organoids of the inner cell mass
Simon Schardt, Sabine C. Fischer
During development, cell fates are determined through a combination of intracellular transcriptional regulations and extracellular signaling. As a result, spatial patterns of diffe…
NANOG/GATA6 Interactions Revisited: A Statistical Mechanics Approach towards Cell Fate Decisions
Simon Schardt, Sabine C. Fischer
In preimplantation mammalian embryos, the second cell fate decision introduces spatial patterns of embryonic and extra-embryonic precursor cells. The transcription factors NANOG an…
On-lattice Vicsek model in confined geometries
Andreas Kuhn, Sabine C. Fischer
The Vicsek model (Vicsek et al. 1995) is a very popular minimalist model to study active matter with a number of applications to biological systems at different length scales. With…