3 papers
stat.ME2026
Principles in harmony: Closed testing meets the partitioning principle for computational efficiency
Werner Brannath, Liane Kluge
We explore and utilize the algorithmic relationship between the closed testing principle for multiple tests with family-wise error rate (FWER) control and the partitioning principl…
stat.ME2026
Informative Simultaneous Confidence Intervals for Graphical Group Sequential Test Procedures
Liane Kluge, Werner Brannath
Test procedures for multiple hypotheses in a group sequential clinical trial that control the family-wise error rate are considered. Several graphical group sequential tests sugges…
stat.ME2025
Adaptive Designs in Fast-Track Registration Processes for Digital Health Applications
Liane Kluge, Werner Brannath
Fast-track procedures play an important role in the context of conditional registration of medical devices, such as listing processes for digital health applications. They offer th…