most citedDynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation

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q-bio.OT2018

A Dynamical Systems Perspective on Chimeric Antigen Receptor T-Cell Dosing

Amir A. Toor, Alden Chesney, Jamal Zweit +2

Chimeric antigen receptor T cells (CAR T cells) are dosed similarly to donor lymphocyte infusions following hematopoietic cell transplantation. In this perspective paper a mathemat…