A Dynamical Systems Perspective on Chimeric Antigen Receptor T-Cell Dosing
arXiv:1805.02796 · doi:10.1038/s41409-018-0329-8.
Abstract
Chimeric antigen receptor T cells (CAR T cells) are dosed similarly to donor lymphocyte infusions following hematopoietic cell transplantation. In this perspective paper a mathematical basis for personalized dosing of CAR T cells is introduced.
4 Pages, 2 Figures