2 citations · 4 across the 3 of their papers we have counts for
3 papers
q-bio.MN2023★ 2 cited
PROSO Toolbox: a unified protein-constrained genome-scale modelling framework for strain designing and optimization
Haoyang Yao, Laurence Yang
The genome-scale metabolic model with protein constraint (PC-model) has been increasingly popular for microbial metabolic simulations. We present PROSO Toolbox, a unified and simpl…
q-bio.QM2018★ 2 cited
Estimating Cellular Goals from High-Dimensional Biological Data
Laurence Yang, Michael A. Saunders, Jean-Christophe Lachance +2
Optimization-based models have been used to predict cellular behavior for over 25 years. The constraints in these models are derived from genome annotations, measured macro-molecul…
q-bio.MN2016
Reliable and efficient solution of genome-scale models of Metabolism and macromolecular Expression
Ding Ma, Laurence Yang, Ronan M. T. Fleming +3
Constraint-Based Reconstruction and Analysis (COBRA) is currently the only methodology that permits integrated modeling of Metabolism and macromolecular Expression (ME) at genome-s…