14 citations · 39 across the 19 of their papers we have counts for
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Feasibility study of the positronium lifetime imaging with the Biograph Vision Quadra and J-PET tomographs
Szymon Parzych, Szymon Niedźwiecki, Ermias Yitayew Beyene +39
Background: After its first ex-vivo and in-vivo demonstration, Positronium Lifetime Imaging (PLI) has received considerable interest as a potential new diagnostic biomarker. High s…
First Positronium Lifetime Imaging using Mn and Co with a plastic-based PET scanner
Manish Das, Sushil Sharma, Ermias Yitayew Beyene +45
Positronium Lifetime Imaging (PLI) extends positron emission tomography by using the lifetime of positronium atoms as a probe of tissue molecular architecture. In this work, we rep…
Patient-specific AI for generation of 3D dosimetry imaging from two 2D-planar measurements
Alejandro Lopez-Montes, Robert Seifert, Astrid Delker +6
In this work we explored the use of patient specific reinforced learning to generate 3D activity maps from two 2D planar images (anterior and posterior). The solution of this probl…
Artificial intelligence for simplified patient-centered dosimetry in radiopharmaceutical therapies
Alejandro Lopez-Montes, Fereshteh Yousefirizi, Yizhou Chen +8
KEY WORDS: Artificial Intelligence (AI), Theranostics, Dosimetry, Radiopharmaceutical Therapy (RPT), Patient-friendly dosimetry KEY POINTS - The rapid evolution of radiopharmaceuti…
First Positronium Lifetime Imaging with Scandium-44 on a Long Axial Field-of-view PET/CT
Lorenzo Mercolli, William M. Steinberger, Pascal V. Grundler +12
Purpose: 44Sc has been successfully produced, synthesized, labeled and first-in-human studies were conducted some years ago. The decay properties of 44Sc, together with being close…
First positronium imaging using Sc with the J-PET scanner: a case study on the NEMA-Image Quality phantom
Manish Das, Sushil Sharma, Aleksander Bilewicz +41
Positronium Lifetime Imaging (PLI), an emerging extension of conventional positron emission tomography (PET) imaging, offers a novel window for probing the submolecular properties…
Positronium Imaging: History, Current Status, and Future Perspectives
Paweł Moskal, Aleksander Bilewicz, Manish Das +11
Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and ox…
Evaluation of Deep Learning-based Scatter Correction on a Long-axial Field-of-view PET scanner
Baptiste Laurent, Alexandre Bousse, Thibaut Merlin +3
Objective: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a…
Positronium Lifetime Imaging with the Biograph Vision Quadra using 124I
Lorenzo Mercolli, William M. Steinberger, Narendra Rathod +7
Purpose: Measuring the ortho-positronium (oPs) lifetime in human tissue bears the potential of adding clinically relevant information about the tissue microenvironment to conventio…
Phantom study for 90Y post-treatment dosimetry with a long axial field-of-view PET/CT
Lorenzo Mercolli, Konstantinos Zeimpekis, George A. Prenosil +3
Purpose: The physical properties of yttrium-90 (90Y) allow for imaging with positron emission tomography/computed tomography (PET/CT). The increased sensitivity of long axial field…
Towards Quality Management of Machine Learning Systems for Medical Applications
Lorenzo Mercolli, Axel Rominger, Kuangyu Shi
The use of machine learning systems in clinical routine is still hampered by the necessity of a medical device certification and/or by difficulty to implement these systems in a cl…