19 citations · 28 across the 11 of their papers we have counts for
12 papers
Dimensionality and confinement reshape competition in cellular renewing active matter
Patrick Zimmer, Philip Bittihn, Yoav G. Pollack
Cellular renewing active matter - assemblies of proliferating and apoptotic cells - underlies tissue homeostasis, morphogenesis, and clonal competition. Previous work in one-dimens…
Orientational lineage memory and mechanical ordering during diffusion-limited growth
Ilias-Marios Sarris, Ramin Golestianian, Philip Bittihn
Growth and shape formation in crowded multicellular assemblies arise from the interplay of chemical gradients, single-cell expansion and mechanical interactions, making it essentia…
Order and shape dependence of mechanical relaxation in proliferating active matter
Jonas Isensee, Lukas Hupe, Philip Bittihn
Collective dynamics in proliferating anisotropic particle systems arise from an interplay between growth, division, and mechanical interactions, often mediated by particle shape. I…
Prediction and control of geometry-induced nematic order in growing multicellular systems
Lukas Hupe, Jonas Isensee, Ramin Golestanian +1
In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientat…
Phase separation in a mixture of proliferating and motile active matter
Lukas Hupe, Joanna M. Materska, David Zwicker +3
Proliferation and motility are ubiquitous drivers of activity in biological systems. Here, we study a dense binary mixture of motile and proliferating particles with exclusively re…
Sensitive particle shape dependence of growth-induced mesoscale nematic structure
Jonas Isensee, Philip Bittihn
Directed growth, anisotropic cell shapes, and confinement drive self-organization in multicellular systems. We investigate the influence of particle shape on the distribution and d…
Isovolumetric dividing active matter
Samantha R. Lish, Lukas Hupe, Ramin Golestanian +1
We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confin…
A minimal model of smoothly dividing disk-shaped cells
Lukas Hupe, Yoav G. Pollack, Jonas Isensee +3
Replication through cell division is one of the most fundamental processes of life and a major driver of dynamics in systems ranging from bacterial colonies to embryogenesis, tissu…
Motility-induced mixing transition in exponentially growing multicellular spheroids
Torben Sunkel, Lukas Hupe, Philip Bittihn
Growth drives cellular dynamics in dense aggregates including bacterial colonies, developing tissues, and tumors. We investigate the underlying physical principles emerging from th…
Collective self-caging of active filaments in virtual confinement
Maximilian Kurjahn, Leila Abbaspour, Franziska Papenfuß +4
Motility coupled to responsive behavior is essential for many microorganisms to seek and establish appropriate habitats. One of the simplest possible responses, reversing the direc…
Stress anisotropy in confined populations of growing rods
Jonas Isensee, Lukas Hupe, Ramin Golestanian +1
Order and alignment are ubiquitous in growing colonies of rod-shaped bacteria due to the nematic properties of the constituent particles. These effects are the result of the active…
Stochastic effects on the dynamics of an epidemic due to population subdivision
Philip Bittihn, Ramin Golestanian
Using a stochastic Susceptible-Infected-Removed (SIR) meta-population model of disease transmission, we present analytical calculations and numerical simulations dissecting the int…