3 papers
stat.ME2025
Correlation Matters! Streamlining the Sample Size Procedure with Composite Time-to-event Endpoints
Yunhan Mou, Fan Li, Denise Esserman +1
Composite endpoints are widely used in cardiovascular clinical trials to improve statistical efficiency while preserving clinical relevance. The Win Ratio (WR) measure and more gen…
stat.ME2020
Estimation of ascertainment bias and its effect on power in clinical trials with time-to-event outcomes
E. J. Greene, P. Peduzzi, J. Dziura +4
While the gold standard for clinical trials is to blind all parties -- participants, researchers, and evaluators -- to treatment assignment, this is not always a possibility. When…
math.ST2018
The maximum negative hypergeometric distribution
Daniel Zelterman
An urn contains a known number of balls of two different colors. We describe the random variable counting the smallest number of draws needed in order to observe at least o…