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physics.bio-ph2025
CTransformer: Deep-transformer-based 3D cell membrane tracking with subcellular-resolved molecular quantification
Zelin Li, Guoye Guan, Xiu Xian +13
Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes invol…
cs.LG2025
DiffeoMorph: Learning to Morph 3D Shapes Using Differentiable Agent-Based Simulations
Seong Ho Pahng, Guoye Guan, Benjamin Fefferman +1
Biological systems can form complex three-dimensional structures through the collective behavior of agents that share a common update rule and operate without central control. How…
eess.IV2025
CellINR: Implicitly Overcoming Photo-induced Artifacts in 4D Live Fluorescence Microscopy
Cunmin Zhao, Ziyuan Luo, Guoye Guan +4
4D live fluorescence microscopy is often compromised by prolonged high intensity illumination which induces photobleaching and phototoxic effects that generate photo-induced artifa…