1 citations · 3 across the 8 of their papers we have counts for
8 papers
Cell size and confinement drive asymmetric cell division through a cortical instability
Da Gao, Guoye Guan, Chao Tang +1
Asymmetric cell division -- in which a mother cell divides into two daughter cells of unequal size -- is a fundamental problem in biology. It is believed that the asymmetry origina…
CTransformer: Deep-transformer-based 3D cell membrane tracking with subcellular-resolved molecular quantification
Zelin Li, Guoye Guan, Xiu Xian +13
Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes invol…
DiffeoMorph: Learning to Morph 3D Shapes Using Differentiable Agent-Based Simulations
Seong Ho Pahng, Guoye Guan, Benjamin Fefferman +1
Biological systems can form complex three-dimensional structures through the collective behavior of agents that share a common update rule and operate without central control. How…
CellINR: Implicitly Overcoming Photo-induced Artifacts in 4D Live Fluorescence Microscopy
Cunmin Zhao, Ziyuan Luo, Guoye Guan +4
4D live fluorescence microscopy is often compromised by prolonged high intensity illumination which induces photobleaching and phototoxic effects that generate photo-induced artifa…
Balancing reaction-diffusion network for cell polarization pattern with stability and asymmetry
Yixuan Chen, Guoye Guan, Lei-Han Tang +1
Cell polarization is a critical process that separates molecular species into two distinct regions in prokaryotic and eukaryotic cells, guiding biological processes such as cell di…
MorphoSim: An efficient and scalable phase-field framework for accurately simulating multicellular morphologies
Xiangyu Kuang, Guoye Guan, Chao Tang +1
The phase field model can accurately simulate the evolution of microstructures with complex morphologies, and it has been widely used for cell modeling in the last two decades. How…
Spontaneous mechanical and energetic state transitions during Caenorhabditis elegans gastrulation
Jiao Miao, Guoye Guan, Chao Tang
Gastrulation, namely cell internalization, is a significant milestone during the development of metazoans from worm to human, which generates multiple embryonic layers with distinc…
Speed and fate diversity tradeoff in nematode's early embryogenesis
Guoye Guan, Ming-Kin Wong, Zhongying Zhao +2
Nematode species are well-known for their invariant cell lineage pattern during development. Combining knowledge about the fate specification induced by asymmetric division and the…