18 citations · 41 across the 10 of their papers we have counts for
3 papers · 1 filter
A phenotype-structured mathematical model for the influence of hypoxia on oncolytic virotherapy
David Morselli, Giulia Chiari, Federico Frascoli +1
The effectiveness of oncolytic virotherapy is significantly affected by several elements of the tumour microenvironment, which reduce the ability of the virus to infect cancer cell…
Multi-scale modeling of Snail-mediated response to hypoxia in tumor progression
Giulia Chiari, Martina Conte, Marcello Delitala
Tumor cell migration within the microenvironment is a crucial aspect for cancer progression and, in this context, hypoxia has a significant role. An inadequate oxygen supply acts a…
A hybrid discrete-continuum modelling approach for the interactions of the immune system with oncolytic viral infections
David Morselli, Marcello E. Delitala, Adrianne L. Jenner +1
Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-cancer immune responses, has garnered significant attention in recent years. In our…