6 papers · 1 filter
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
Gelation dynamics upon pressure-induced liquid-liquid phase separation in a water-lysozyme solution
M. Moron, A. Al-Masoodi, C. Lovato +9
Employing X-ray photon correlation spectroscopy we measure the kinetics and dynamics of a pressure-induced liquid-liquid phase separation (LLPS) in a water-lysozyme solution. Scatt…
Using low dose X-ray Speckle Visibility Spectroscopy to study dynamics of soft matter samples
Johannes Möller, Mario Reiser, Jörg Hallmann +10
We demonstrate the successful application of X-ray Speckle Visibility Spectroscopy (XSVS) experiments to study the dynamics of radiation sensitive, biological samples with unpreced…
Automated matching of two-time X-ray photon correlation maps from protein dynamics with Cahn-Hilliard type simulations using autoencoder networks
S. Timmermann, V. Starostin, A. Girelli +10
We use machine learning methods for an automated classification of experimental XPCS two-time correlation functions from an arrested liquid-liquid phase separation of a protein sol…
Nanoscale Rigidity in Cross-Linked Micelle Networks Revealed by XPCS Nanorheology
M. Reiser, J. Hallmann, J. Möller +11
Solutions of wormlike micelles can form cross-linked networks on microscopic length scales. The unique mechanical properties of these complex fluids are driven by the interplay bet…