38 citations · 119 across the 11 of their papers we have counts for
12 papers
Nanoscale Protein Diffusion in Supercooled Cryoprotectant Solutions
Maddalena Bin, Anita Girelli, Mariia Filianina +15
Vitrification during cryopreservation requires a quantitative understanding of protein transport in deeply supercooled cryoprotectant solutions, yet direct measurements at molecula…
Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions
Anita Girelli, Maddalena Bin, Mariia Filianina +38
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affe…
Nanocrystallites Modulate Intermolecular Interactions in Cryoprotected Protein Solutions
Mariia Filianina, Maddalena Bin, Sharon Berkowicz +7
Studying protein interactions at low temperatures has important implications for optimizing cryostorage processes of biological tissue, food, and protein-based drugs. One of the ma…
Coherent X-ray Scattering Reveals Nanoscale Fluctuations in Hydrated Proteins
Maddalena Bin, Mario Reiser, Mariia Filianina +15
Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investiga…
Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
Mario Reiser, Anita Girelli, Anastasia Ragulskaya +26
X-ray free-electron lasers (XFELs) with megahertz repetition rate can provide novel insights into structural dynamics of biological macromolecule solutions. However, very high dose…
Gelation dynamics upon pressure-induced liquid-liquid phase separation in a water-lysozyme solution
M. Moron, A. Al-Masoodi, C. Lovato +9
Employing X-ray photon correlation spectroscopy we measure the kinetics and dynamics of a pressure-induced liquid-liquid phase separation (LLPS) in a water-lysozyme solution. Scatt…
Using low dose X-ray Speckle Visibility Spectroscopy to study dynamics of soft matter samples
Johannes Möller, Mario Reiser, Jörg Hallmann +10
We demonstrate the successful application of X-ray Speckle Visibility Spectroscopy (XSVS) experiments to study the dynamics of radiation sensitive, biological samples with unpreced…
Automated matching of two-time X-ray photon correlation maps from protein dynamics with Cahn-Hilliard type simulations using autoencoder networks
S. Timmermann, V. Starostin, A. Girelli +10
We use machine learning methods for an automated classification of experimental XPCS two-time correlation functions from an arrested liquid-liquid phase separation of a protein sol…
Interplay between Kinetics and Dynamics of Liquid-Liquid Phase Separation in a Protein Solution Revealed by Coherent X-ray Spectroscopy
Anastasia Ragulskaya, Nafisa Begam, Anita Girelli +7
Microscopic dynamics of complex fluids in the early stage of spinodal decomposition (SD) is strongly intertwined with the kinetics of structural evolution, which makes a quantitati…
Nanoscale Rigidity in Cross-Linked Micelle Networks Revealed by XPCS Nanorheology
M. Reiser, J. Hallmann, J. Möller +11
Solutions of wormlike micelles can form cross-linked networks on microscopic length scales. The unique mechanical properties of these complex fluids are driven by the interplay bet…
Ultrafast molecular orbital tomography of a pentacene thin film using time-resolved momentum microscopy at a free-electron laser
K. Baumgärtner, M. Reuner, C. Metzger +19
We use time-resolved momentum microscopy at a free-electron laser (FEL) and extend orbital tomography into the time domain to image the electronic wave functions of excited molecul…
Low dose X-ray speckle visibility spectroscopy reveals nanoscale dynamics in radiation sensitive ionic liquids
Jan Verwohlt, Mario Reiser, Lisa Randolph +6
X-ray radiation damage provides a serious bottle neck for investigating μs to s dynamics on nanometer length scales employing X-ray photon correlation spectroscopy. This limitation…