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20192025
most citedRawHash: Enabling Fast and Accurate Real-Time Analysis of Raw Nanopore Signals for Large Genomes

46 citations · 104 across the 26 of their papers we have counts for

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11 papers · 1 filter

q-bio.GN2025

RawBench: A Comprehensive Benchmarking Framework for Raw Nanopore Signal Analysis Techniques

Furkan Eris, Ulysse McConnell, Can Firtina +1

Nanopore sequencing technologies continue to advance rapidly, offering critical benefits such as real-time analysis, the ability to sequence extremely long DNA fragments (up to mil…

q-bio.GN2024

Rawsamble: Overlapping and Assembling Raw Nanopore Signals using a Hash-based Seeding Mechanism

Can Firtina, Maximilian Mordig, Harun Mustafa +7

Raw nanopore signal analysis is a common approach in genomics to provide fast and resource-efficient analysis without translating the signals to bases (i.e., without basecalling).…

q-bio.GN2023

MetaTrinity: Enabling Fast Metagenomic Classification via Seed Counting and Edit Distance Approximation

Arvid E. Gollwitzer, Mohammed Alser, Joel Bergtholdt +5

Metagenomics, the study of genome sequences of diverse organisms cohabiting in a shared environment, has experienced significant advancements across various medical and biological…

q-bio.GN2023

SequenceLab: A Comprehensive Benchmark of Computational Methods for Comparing Genomic Sequences

Maximilian-David Rumpf, Mohammed Alser, Arvid E. Gollwitzer +5

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational…

q-bio.GN2023★ 2 cited

RawAlign: Accurate, Fast, and Scalable Raw Nanopore Signal Mapping via Combining Seeding and Alignment

Joël Lindegger, Can Firtina, Nika Mansouri Ghiasi +3

Nanopore sequencers generate raw electrical signals representing the contents of a biological sequence molecule passing through the nanopore. These signals can be analyzed directly…

q-bio.GN2023★ 19 cited

RawHash2: Mapping Raw Nanopore Signals Using Hash-Based Seeding and Adaptive Quantization

Can Firtina, Melina Soysal, Joël Lindegger +1

Summary: Raw nanopore signals can be analyzed while they are being generated, a process known as real-time analysis. Real-time analysis of raw signals is essential to utilize the u…