Showing 2026Show all
3 papers · 1 filter
stat.ME2026
Exact association-test distributions for prior-informed stepwise SNP prioritization
N. Kossi Doulabe, Anne-Sophie Charest, Lajmi Lakhal-Chaieb
Prioritizing causal variants in Genome-Wide Association Studies (GWAS) is challenging due to linkage disequilibrium and high dimensionality. We propose an iterative algorithm for t…
stat.ME2026
Risk prediction models for breast cancer integrating family history of breast cancer and prophylactic interventions
Siriac Seboka, Laurent Briollais, Yun-Hee Choi +2
Breast cancer risk assessment and prediction models are very important tools for the clinical management of healthy women carrying pathogenic variants in known cancer genes. We pro…
stat.ME2026
Global testing of SNP-methylation interactions on binary phenotypes via a logistic functional regression model
Yvelin Gansou, Karim Oualkacha, Marzia Angela Cremona +1
Understanding how genetic and epigenetic factors jointly influence binary health outcomes remains a major challenge in biomedical research. We propose a global test for the overall…