71 citations · 74 across the 4 of their papers we have counts for
3 papers · 1 filter
Designing biological circuits: from principles to applications
Debomita Chakraborty, Raghunathan Rengaswamy, Karthik Raman
Genetic circuit design is a well-studied problem in synthetic biology. Ever since the first genetic circuits -- the repressilator and the toggle switch -- were designed and impleme…
Effect of Dormant Spare Capacity on the Attack Tolerance of Complex Networks
Sai Saranga Das M, Karthik Raman
The vulnerability of networks to targeted attacks is an issue of widespread interest for policymakers, military strategists, network engineers and systems biologists alike. Current…
Fast-SL: An efficient algorithm to identify synthetic lethal reaction sets in metabolic networks
Aditya Pratapa, Shankar Balachandran, Karthik Raman
Synthetic lethal reaction/gene-sets are sets of reactions/genes where only the simultaneous removal of all reactions/genes in the set abolishes growth of an organism. In silico, sy…