71 citations · 74 across the 4 of their papers we have counts for
5 papers
Designing biological circuits: from principles to applications
Debomita Chakraborty, Raghunathan Rengaswamy, Karthik Raman
Genetic circuit design is a well-studied problem in synthetic biology. Ever since the first genetic circuits -- the repressilator and the toggle switch -- were designed and impleme…
Effect of Dormant Spare Capacity on the Attack Tolerance of Complex Networks
Sai Saranga Das M, Karthik Raman
The vulnerability of networks to targeted attacks is an issue of widespread interest for policymakers, military strategists, network engineers and systems biologists alike. Current…
The art of molecular computing: whence and whither
Sahana Gangadharan, Karthik Raman
An astonishingly diverse biomolecular circuitry orchestrates the functioning machinery underlying every living cell. These biomolecules and their circuits have been engineered not…
Goal directed molecule generation using Monte Carlo Tree Search
Anand A. Rajasekar, Karthik Raman, Balaraman Ravindran
One challenging and essential task in biochemistry is the generation of novel molecules with desired properties. Novel molecule generation remains a challenge since the molecule sp…
Fast-SL: An efficient algorithm to identify synthetic lethal reaction sets in metabolic networks
Aditya Pratapa, Shankar Balachandran, Karthik Raman
Synthetic lethal reaction/gene-sets are sets of reactions/genes where only the simultaneous removal of all reactions/genes in the set abolishes growth of an organism. In silico, sy…