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q-bio.GN2021
COSINE: A Web Server for Clonal and Subclonal Structure Inference and Evolution in Cancer Genomics
Xiguo Yuan, Yuan Zhao, Yang Guo +10
Cancers evolve from mutation of a single cell with sequential clonal and subclonal expansion of somatic mutation acquisition. Inferring clonal and subclonal structures from bulk or…
q-bio.GN2012
Integrating Prior Knowledge Into Prognostic Biomarker Discovery based on Network Structure
Yupeng Cun, Holger Fröhlich
Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various meth…