120 citations · 634 across the 9 of their papers we have counts for
9 papers
A versatile multicomponent mesoporous silica nanosystem with dual antimicrobial and osteogenic effects
Elena Alvarez, Manuel Estevez, Carla Jimenez-Jimenez +4
In this manuscript, we propose a simple and versatile methodology to design nanosystems based on biocompatible and multicomponent mesoporous silica nanoparticles (MSNs) for infecti…
Effective reduction of biofilm through photothermal therapy by gold core@shell based mesoporous silica nanoparticles
Ana Garcia, Blanca Gonzalez, Catherine Harvey +2
Bacterial biofilms can initiate chronic infections that become difficult to eradicate. There is an unmet need for effective therapeutic strategies that control and inhibit the grow…
Strontium-releasing mesoporous bioactive glasses with anti-adhesive zwitterionic surface as advanced biomaterials for bone tissue regeneration
Carlotta Pontremoli, Isabel Izquierdo-Barba, Giorgia Montalbano +3
Hypothesis The treatment of bone fractures still represents a challenging clinical issue when complications due to impaired bone remodelling (i.e. osteoporosis) or infections occur…
Mixed-charge pseudo-zwitterionic mesoporous silica nanoparticles with lowfouling and reduced cell uptake properties
Noemi Encinas, Mercedes Angulo, Carlos Astorga +3
The design of drug delivery systems needs to consider biocompatibility and host body recognition for an adequate actuation. In this work, mesoporous silica nanoparticles (MSNs) sur…
Mesoporous Silica Nanoparticles Decorated with Polycationic Dendrimers for Infection Treatment
Blanca Gonzalez, Montserrat Colilla, Jaime Diez +4
This work aims to provide an effective and novel solution for the treatment of infection by using nanovehicles loaded with antibiotics capable of penetrating the bacterial wall, th…
Impact of the antibiotic-cargo from MSNs on Gram-positive and Gram-negative bacterial biofilms
Anna Aguilar-Colomer, Montserrat Colilla, Isabel Izquierdo-Barba +4
Mesoporous silica nanoparticles (MSNs) are promising drug nanocarriers for infection treatment. Many investigations have focused on evaluating the capacity of MSNs to encapsulate a…
Concanavalin A-targeted mesoporous silica nanoparticles for infection treatment
Marina Martinez-Carmona, Isabel Izquierdo-Barba, Montserrat Colilla +1
The ability of bacteria to form biofilms hinders any conventional treatment against chronic infections and has serious socio-economic implications. In this sense, a nanocarrier cap…
3D scaffold with effective multidrug sequential release against bacteria biofilm
Rafaela Garcia-Alvarez, Isabel Izquierdo-Barba, Maria Vallet-Regi
Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved wi…
Synergistic effect of Si-hydroxyapatite coating and VEGF adsorption on Ti6Al4V-ELI scaffolds for bone regeneration in an osteoporotic bone environment
I. Izquierdo-Barba, L. Santos-Ruiz, J. Becerra +12
The osteogenic and angiogenic responses to metal macroporous scaffolds coated with silicon substituted hydroxyapatite (SiHA) and decorated with vascular endothelial growth factor (…