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cond-mat.soft2026
From biting to engulfment: Target mechanics determines modes of phagocytosis through curvature--actin coupling
Shubhadeep Sadhukhan, Caitlin E. Cornell, Mansehaj Kaur Sandhu +10
Phagocytosis is a core innate immune process that clears targets spanning a wide range of mechanical properties, yet the role of target mechanics in recognition and engulfment rema…
cond-mat.soft2023
Modelling how curved active proteins and shear flow pattern cellular shape and motility
Shubhadeep Sadhukhan, Samo Penič, Aleš Iglič +1
Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membr…
cond-mat.soft2023
Theoretical model of membrane protrusions driven by curved active proteins
Yoav Ravid, Samo Penič, Yuko Mimori-Kiyosue +3
Eukaryotic cells intrinsically change their shape, by changing the composition of their membrane and by restructuring their underlying cytoskeleton. We present here further studies…