activity
20152025
most citedKinetic Selection of Template Polymer with Complex Sequences

20 citations · 47 across the 6 of their papers we have counts for

collaborators

6 papers

q-bio.PE2025★ 1 cited

Suppression of errors in collectively coded information

Martin J. Falk, Leon Zhou, Yoshiya J. Matsubara +3

Modern life largely transmits genetic information from mother to daughter through the duplication of single physically intact molecules that encode information. However, copying an…

physics.bio-ph2022★ 3 cited

Conditions for Darwinian evolution in compartmentalized autocatalytic reaction networks

Yoshiya J. Matsubara, Sandeep Ameta, Shashi Thutupalli +2

The first forms of life likely consisted of protocells endowed with metabolism, growth, and division. Such systems may have evolved due to variation and heredity in their chemical…

physics.bio-ph2021

Error Catastrophe Can Be Avoided by Proofreading Innate to Template-Directed Polymerization

Yoshiya J. Matsubara, Nobuto Takeuchi, Kunihiko Kaneko

An important issue for the origins of life is ensuring the accurate maintenance of information in replicating polymers in the face of inevitable errors. Here, we investigated how t…

q-bio.CB2019★ 11 cited

Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes

Atsushi Kamimura, Yoshiya J. Matsubara, Kunihiko Kaneko +1

The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polyme…

physics.bio-ph2018★ 20 cited

Kinetic Selection of Template Polymer with Complex Sequences

Yoshiya J. Matsubara, Kunihiko Kaneko

Emergence and maintenance of polymers with complex sequences is a major question in the study of origins of life. To answer this, we studied a model polymerization reaction, where…

physics.chem-ph2015★ 12 cited

Optimal size for emergence of self-replicating polymer system

Yoshiya J. Matsubara, Kunihiko Kaneko

A biological system consists of a variety of polymers that are synthesized from monomers, by catalysis that exists only for some long polymers. It is important to elucidate the eme…