2 papers
q-bio.MN2019
Stochastic modelling reveals mechanisms of metabolic heterogeneity
Mona K. Tonn, Philipp Thomas, Mauricio Barahona +1
Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth varia…
q-bio.MN2016
Flux-dependent graphs for metabolic networks
Mariano Beguerisse-Díaz, Gabriel Bosque, Diego Oyarzún +2
Cells adapt their metabolic fluxes in response to changes in the environment. We present a framework for the systematic construction of flux-based graphs derived from organism-wide…