159 citations · 414 across the 11 of their papers we have counts for
12 papers
The Physics of Stratum Corneum Lipid Membranes
Chinmay Das, Peter D. Olmsted
The Stratum Corneum (SC), the outermost layer of skin, comprises rigid corneocytes (keratin filled dead cells) in a specialized lipid matrix. The continuous lipid matrix provides t…
Fast cholesterol flip-flop and lack of swelling in skin lipid multilayers
Chinmay Das, Massimo G. Noro, Peter D. Olmsted
Atomistic simulations were performed on hydrated model lipid multilayers that are representative of the lipid matrix in the outer skin (stratum corneum). We find that cholesterol t…
Lamellar and inverse micellar structures of skin lipids: Effect of templating
Chinmay Das, Massimo G. Noro, Peter D. Olmsted
The outermost layer of skin, the stratum corneum (SC), comprises rigid corneocytes in a layered lipid matrix. Using atomistic simulations we find that the equilibrium phase of the…
Nano-scale mechanical probing of supported lipid bilayers with atomic force microscopy
Chinmay Das, Khizar H. Sheik, Peter D. Olmsted +1
We present theory and experiments for the force-distance curve of an atomic force microscope (AFM) tip (radius ) indenting a supported fluid bilayer (thickness ). F…
Water permeation through stratum corneum lipid bilayers from atomistic simulations
Chinmay Das, Peter D. Olmsted, Massimo G. Noro
Stratum corneum, the outermost layer of skin, consists of keratin filled rigid non-viable corneocyte cells surrounded by multilayers of lipids. The lipid layer is responsible for t…
Simulation studies of stratum corneum lipid mixtures
Chinmay Das, Massimo G. Noro, Peter D. Olmsted
We present atomistic molecular dynamics results for fully hydrated bilayers composed of ceramide NS-24:0, free fatty acid 24:0 and cholesterol, to address the effect of the differe…