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physics.bio-ph2021
Coordinated tractions increase the size of a collectively moving pack in a cell monolayer
Aashrith Saraswathibhatla, Silke Henkes, Emmett E. Galles +2
Cells in an epithelial monolayer coordinate motion with their neighbors giving rise to collectively moving packs of sizes spanning multiple cell diameters. The physical mechanism c…
physics.bio-ph2019
Cells exploit a phase transition to mechanically remodel the fibrous extracellular matrix
Georgios Grekas, Maria Proestaki, Phoebus Rosakis +3
Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers-tracts of high densification and fiber align…
physics.bio-ph2019
Tractions and stress fibers control cell shape and rearrangements in collective cell migration
Aashrith Saraswathibhatla, Jacob Notbohm
Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearr…