106 citations · 277 across the 6 of their papers we have counts for
6 papers
Coordinated tractions increase the size of a collectively moving pack in a cell monolayer
Aashrith Saraswathibhatla, Silke Henkes, Emmett E. Galles +2
Cells in an epithelial monolayer coordinate motion with their neighbors giving rise to collectively moving packs of sizes spanning multiple cell diameters. The physical mechanism c…
Cells exploit a phase transition to mechanically remodel the fibrous extracellular matrix
Georgios Grekas, Maria Proestaki, Phoebus Rosakis +3
Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers-tracts of high densification and fiber align…
Biomechanics of Collective Cell Migration in Cancer Progression -- Experimental and Computational Methods
Catalina-Paula Spatarelu, Hao Zhang, Dung Trung Nguyen +7
Cell migration is essential for regulating many biological processes in physiological or pathological conditions, including embryonic development and cancer invasion. In vitro and…
Tractions and stress fibers control cell shape and rearrangements in collective cell migration
Aashrith Saraswathibhatla, Jacob Notbohm
Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearr…
A Model for Compression-Weakening Materials and the Elastic Fields due to Contractile Cells
Phoebus Rosakis, Jacob Notbohm, Guruswami Ravichandran
We construct a homogeneous, nonlinear elastic constitutive law, that models aspects of the mechanical behavior of inhomogeneous fibrin networks. Fibers in such networks buckle when…
Microbuckling of Fibrin Provides a Mechanism for Cell Mechanosensing
Jacob Notbohm, Ayelet Lesman, Phoebus Rosakis +2
Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show tha…