52 citations · 52 across the 4 of their papers we have counts for
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q-bio.CB2011
Timing is everything: on the stochastic origins of cell-to-cell variability in cancer cell death decisions
Joanna Skommer, Subhadip Raychaudhuri, Donald Wlodkowic
The diversity of cell populations is regulated by extracellular and intracellular variability. The latter includes genetic, epigenetic and stochastic variability, all contributing…
q-bio.CB2010
Discrimination of Membrane Antigen Affinity by B cells Requires Dominance of Kinetic Proofreading over Serial Triggering
Philippos K. Tsourkas, Wanli Liu, Somkanya C Das +2
B cells receptor (BCR) signaling in response to membrane-bound antigen increases with antigen affinity, a process known as affinity discrimination. We use computational modeling to…