89 citations · 99 across the 9 of their papers we have counts for
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q-bio.TO2022★ 1 cited
In-vitro to in-vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmaco-dynamic models and a multiscale spatial-temporal liver twin
Jules Dichamp, Geraldine Cellière, Ahmed Ghallab +8
In vitro to in vivo extrapolation represents a critical challenge in toxicology. In this paper we explore extrapolation strategies for acetaminophen (APAP) based on mechanistic mod…
q-bio.TO2020★ 1 cited
Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy
Stefan Hoehme, Rolf Gebhardt, Jan G. Hengstler +1
Partial hepatectomy (PHx) is a surgical intervention where a part of the liver is removed. Due to its extraordinary capacity to regenerate, the liver is able to regenerate about tw…